Magnetic Resonance Imaging
Volume 24, Issue 1 , Pages 69-74 , January 2006

Spectroscopic imaging of the brain with phased-array coils at 3.0 T

  • Duan Xu

      Affiliations

    • Joint UCSF/UCB Graduate Group in Bioengineering, University of California, San Francisco and Berkeley, CA 94143, USA
    • Department of Radiology, University of California, San Francisco, CA 94143-2512, USA
    • Corresponding Author InformationCorresponding author. Department of Radiology, University of California, Box 2512, San Francisco, CA 94143-2512, USA. Tel.: +1 415 514 4455; fax: +1 415 513 4450.
    • ,
  • Albert P. Chen

      Affiliations

    • Joint UCSF/UCB Graduate Group in Bioengineering, University of California, San Francisco and Berkeley, CA 94143, USA
    • Department of Radiology, University of California, San Francisco, CA 94143-2512, USA
    • ,
  • Charles Cunningham

      Affiliations

    • Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA
    • ,
  • Joseph A. Osorio

      Affiliations

    • Joint UCSF/UCB Graduate Group in Bioengineering, University of California, San Francisco and Berkeley, CA 94143, USA
    • Department of Radiology, University of California, San Francisco, CA 94143-2512, USA
    • ,
  • Sarah J. Nelson

      Affiliations

    • Joint UCSF/UCB Graduate Group in Bioengineering, University of California, San Francisco and Berkeley, CA 94143, USA
    • Department of Radiology, University of California, San Francisco, CA 94143-2512, USA
    • ,
  • Daniel B. Vigneron

      Affiliations

    • Joint UCSF/UCB Graduate Group in Bioengineering, University of California, San Francisco and Berkeley, CA 94143, USA
    • Department of Radiology, University of California, San Francisco, CA 94143-2512, USA

Received 2 August 2005 ,Accepted 19 October 2005.

References 

  1. Nelson SJ. Multivoxel magnetic resonance spectroscopy of brain tumors. Mol Cancer Ther. 2003;2(5):497–507
  2. Kurhanewicz J, Vigneron DB, Nelson SJ. Three-dimensional magnetic resonance spectroscopic imaging of brain and prostate cancer. Neoplasia. 2000;2(1–2):166–189
  3. Noworolski SM, et al. High spatial resolution 1H-MRSI and segmented MRI of cortical gray matter and subcortical white matter in three regions of the human brain. Magn Reson Med. 1999;41(1):21–29
  4. Florian CL, et al. Regional and developmental variations in metabolite concentration in the rat brain and eye: a study using 1H NMR spectroscopy and high performance liquid chromatography. Neurochem Res. 1996;21(9):1065–1074
  5. Koller KJ, Zaczek R, Coyle JT. N-acetyl-aspartyl-glutamate: regional levels in rat brain and the effects of brain lesions as determined by a new HPLC method. J Neurochem. 1984;43(4):1136–1142
  6. Urenjak J, et al. Proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types. J Neurosci. 1993;13(3):981–989
  7. Wald LL, et al. Proton spectroscopic imaging of the human brain using phased array detectors. Magn Reson Med. 1995;34(3):440–445
  8. Schricker AA, et al. Dualband spectral-spatial RF pulses for prostate MR spectroscopic imaging. Magn Reson Med. 2001;46(6):1079–1087
  9. Srinivasan R, et al. A comparative study of myo-inositol quantification using LC model at 1.5 T and 3.0 T with 3 D H-1 proton spectroscopic imaging of the human brain. Magn Reson Imaging. 2004;22(4):523–528
  10. Hurd R, et al. Measurement of brain glutamate using TE-averaged PRESS at 3T. Magn Reson Med. 2004;51(3):435–440
  11. Males RG, et al. Clinical application of BASING and spectral/spatial water and lipid suppression pulses for prostate cancer staging and localization by in vivo 3D 1H magnetic resonance spectroscopic imaging. Magn Reson Med. 2000;43(1):17–22
  12. Cunningham CH, et al. Design of symmetric-sweep spectral-spatial RF pulses for spectral editing. Magn Reson Med. 2004;52(1):147–153
  13. Maudsley AA, et al. Reduced phase encoding in spectroscopic imaging. Magn Reson Med. 1994;31(6):645–651
  14. Tedeschi G, et al. Brain regional distribution pattern of metabolite signal intensities in young adults by proton magnetic resonance spectroscopic imaging. Neurology. 1995;45(7):1384–1391
  15. Chang L, Cloak CC, Ernst T. Magnetic resonance spectroscopy studies of GABA in neuropsychiatric disorders. J Clin Psychiatry. 2003;64(Suppl 3):7–14
  16. Ure JA, Perassolo M. Update on the pathophysiology of the epilepsies. J Neurol Sci. 2000;177(1):1–17
  17. Barkovich AJ. In: Normal development, in pediatric neuroimaging. Philadelphia: Lippincott Williams and Wilkins; 2000;p. 13–69

☆ This work was supported by grants from the National Institutes of Health (RO1 NS40117 and UC Discovery LSIT 01-10107).

PII: S0730-725X(05)00324-3

doi: 10.1016/j.mri.2005.10.019

Magnetic Resonance Imaging
Volume 24, Issue 1 , Pages 69-74 , January 2006

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