Magnetic Resonance Imaging
Volume 26, Issue 10 , Pages 1360-1366, December 2008

An optimized 3D inversion recovery prepared fast spoiled gradient recalled sequence for carotid plaque hemorrhage imaging at 3.0 T☆

  • David C. Zhu

      Affiliations

    • Department of Radiology, Michigan State University, East Lansing, MI 48824, USA
    • Department of Psychology, Michigan State University, East Lansing, MI 48824, USA
    • Cognitive Imaging Research Center, Michigan State University, East Lansing, MI 48824, USA
    • Corresponding Author InformationCorresponding author. Michigan State University, East Lansing, MI 48824, USA. Tel.: +1 517 353 9432; fax: +1 517 353 3745.
    • ,
  • Marina S. Ferguson

      Affiliations

    • Vascular Imaging Lab, University of Washington, Seattle, WA 98109, USA
    • ,
  • J. Kevin DeMarco

      Affiliations

    • Department of Radiology, Michigan State University, East Lansing, MI 48824, USA

Received 31 January 2008; received in revised form 2 May 2008; accepted 2 May 2008. published online 26 June 2008.

Abstract 

An optimized 3D inversion recovery prepared fast spoiled gradient recalled sequence (IR FSPGR) on a 3-T scanner for carotid plaque imaging is described. It offers clear blood and fat signal suppression at the carotid artery bifurcation and highlights the regions of carotid plaque affected by hemorrhage at 3 T with high contrast and contrast-to-noise ratio compared with other sequences. It can potentially be used to replace the more traditional noncontrast T1-weighted 2D black-blood imaging for hemorrhage detection and offers additional benefits of high-resolution 3D volumetric visualization.

Keywords: 3D IR FSPGR, Carotid plaque imaging

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☆ Grant support: The Core Analytical Facility Fund and an IRGP grant from Michigan State University, an extramural research grant from Bracco Diagnostic, Inc., and financial support from GE Healthcare Systems.

PII: S0730-725X(08)00147-1

doi:10.1016/j.mri.2008.05.002

Magnetic Resonance Imaging
Volume 26, Issue 10 , Pages 1360-1366, December 2008

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