Magnetic Resonance Imaging
Volume 27, Issue 9 , Pages 1242-1248 , November 2009

In vivo structural analysis of articular cartilage using diffusion tensor magnetic resonance imaging

  • Takashi Azuma

      Affiliations

    • Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81 75 751 4132; fax: +81 75 751 4132.
    • ,
  • Ryusuke Nakai

      Affiliations

    • Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan
    • ,
  • Osamu Takizawa

      Affiliations

    • Medical Solutions Marketing Division, Siemens-Asahi Medical Technologies Ltd., Tokyo, Japan
    • ,
  • Sadami Tsutsumi

      Affiliations

    • Nihon University School of Dentistry, Tokyo, Japan

Received 3 July 2008 ,Revised 1 April 2009 ,Accepted 7 May 2009.

References 

  1. Stejskal EO, Tanner JE. Spin diffusion measurements — spin echoes in presence of a time-dependent field gradient. J Chem Phys. 1965;42(1):288–292
  2. Le Bihan D, et al. MR Imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology. 1986;161(2):401–407
  3. Cleveland GG, Chang DC, Hazelwood CF. Nuclear magnetic resonance measurements of skeletal muscle. Anisotropy of the diffusion coefficient of the intracellular water. Biophys J. 1976;16:1043–1053
  4. Moseley ME, Cohen Y, Kucharczyk J. Diffusion-weighted MR imaging of anisotropic water diffusion in cat central nervous system. Radiology. 1990;176:439–446
  5. Chenevert TL, Brunberg JA, Pipe JG. Anisotropic diffusion within human white matter: demonstration with NMR techniques in vivo. Radiology. 1990;177:401–405
  6. Turner R, Le Bihan D, Maier J. Echo-planar imaging of intravoxel incoherent motions. Radiology. 1990;177:407
  7. Lythgoe MF, Busza AL, Calamante F. Effects of diffusion anisotropy on lesion delineation in a rat model of cerebral ischemia. Magn Reson Med. 1997;38:662–668
  8. Hoehn Berlage M, Eis M, Schmitz B. Regional and directional anisotropy of apparent diffusion coefficient in rat brain. NMR Biomed. 1999;12:45–50
  9. Douek P, et al. MR Color mapping of myelin fiber orientation. J Comput Assist Tomogr. 1991;15:923–929
  10. Basser PJ, Mattiello J, LeBihan D. Estimation of the effective self-diffusion tensor from the NMR spin echo. J Magn Reson B. 1994;103(3):247–254
  11. Basser PJ, Mattiello J, Le Bihan D. MR Diffusion tensor spectroscopy and imaging. Biophys J. 1994;66:259–267
  12. Pierpaoli C, et al. Diffusion tensor MR imaging of the human brain. Radiology. 1996;201(3):637–648
  13. Basser PJ, Pierpaoli C. A simplified method to measure the diffusion tensor from seven MR images. Magn Reson Med. 1998;39(6):928–934
  14. Jones DK, Horsfield MA, Simmons A. Optimal strategies for measuring diffusion in anisotropic systems by magnetic resonance imaging. Magn Reson Med. 1999;42(3):515–525
  15. Le Bihan D, et al. Diffusion tensor imaging: concepts and applications. J Magn Reson Imaging. 2001;13(4):534–546
  16. Buckwalter JA, Mankin HJ. Articular cartilage: tissue design and chondrocyte-matrix interactions. Instr Course Lect. 1998;47:477–486
  17. Clarke IC. Articular cartilage: a review and scanning electron microscope study: 1. The interterritorial fibrillar architecture. J Bone Joint Surg Br. 1971;53(4):732–750
  18. Glaser C, Putz R. Functional anatomy of articular cartilage under compressive loading quantitative aspects of global, local and zonal reactions of the collagenous network with respect to the surface integrity. Osteoarthritis Cartilage. 2002;10(2):83–99
  19. Le Bihan D. Intravoxel incoherent motion imaging using steady-state free precession. Magn Reson Med. 1988;7(3):346–351
  20. Nieminen MT, et al. T2 relaxation reveals spatial collagen architecture in articular cartilage: a comparative quantitative MRI and polarized light microscopic study. Magn Reson Med. 2001;46(3):487–493
  21. Wakitani S, et al. Repair of large full-thickness articular cartilage defects with allograft articular chondrocytes embedded in a collagen gel. Tissue Eng. 1998;4(4):429–444
  22. Burstein D, et al. Diffusion of small solutes in cartilage as measured by nuclear magnetic resonance (NMR) spectroscopy and imaging. J Orthop Res. 1993;11(4):465–478
  23. Xia Y, et al. Self-diffusion monitors degraded cartilage. Arch Biochem Biophys. 1995;323(2):323–328
  24. Knauss R, et al. Self-diffusion of water in cartilage and cartilage components as studied by pulsed field gradient NMR. Magn Reson Med. 1999;41(2):285–292
  25. Mlynarik V, et al. Investigation of apparent diffusion constant as an indicator of early degenerative disease in articular cartilage. J Magn Reson Imaging. 2003;17(4):440–444
  26. Filidoro L, et al. High-resolution diffusion tensor imaging of human patellar cartilage: feasibility and preliminary findings. Magn Reson Med. 2005;53(5):993–998
  27. Meder R, et al. Diffusion tensor imaging of articular cartilage as a measure of tissue microstructure. Osteoarthritis Cartilage. 2006;14(9):875–881
  28. Deng X, et al. Diffusion tensor imaging of native and degenerated human articular cartilage. Magn Reson Imaging. 2007;25(2):168–171
  29. de Visser SK, Crawford RW, Pope JM. Structural adaptations in compressed articular cartilage measured by diffusion tensor imaging. Osteoarthritis Cartilage. 2007;
  30. Stehling MK, Turner R, Mansfield P. Echo-planar imaging: magnetic resonance imaging in a fraction of a second. Science. 1991;254(5028):43–50
  31. Reese TG, et al. Reduction of eddy-current-induced distortion in diffusion MRI using a twice-refocused spin echo. Magn Reson Med. 2003;49(1):177–182
  32. Griswold MA, et al. Generalized autocalibrating partially parallel acquisitions (GRAPPA). Magn Reson Med. 2002;47(6):1202–1210
  33. Mlynarik V, et al. The role of relaxation times in monitoring proteoglycan depletion in articular cartilage. J Magn Reson Imaging. 1999;10(4):497–502
  34. Mosher TJ, Dardzinski BJ, Smith MB. Human articular cartilage: influence of aging and early symptomatic degeneration on the spatial variation of T2–preliminary findings at 3 T. Radiology. 2000;214(1):259–266
  35. Buckwalter JA, Mankin HJ. Articular cartilage: degeneration and osteoarthritis, repair, regeneration, and transplantation. Instr Course Lect. 1998;47:487–504

PII: S0730-725X(09)00092-7

doi: 10.1016/j.mri.2009.05.012

Magnetic Resonance Imaging
Volume 27, Issue 9 , Pages 1242-1248 , November 2009

Article Tools

* Image Usage & Resolution