Analysis of hyperpolarized dynamic 13C lactate imaging in a transgenic mouse model of prostate cancer

Lupo, Janine M.; Chen, Albert P.; Zierhut, Matthew L.; Bok, Robert A.; Cunningham, Charles H.; Kurhanewicz, John; Vigneron, Daniel B.; Nelson, Sarah J.

doi:10.1016/j.mri.2009.07.007

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Volume 28, Issue 2 , Pages 153-162, February 2010

Analysis of hyperpolarized dynamic ¹³C lactate imaging in a transgenic mouse model of prostate cancer ☆

Janine M. Lupo
- Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA
- Corresponding author. UCSF Radiology, Box 2532, San Francisco, CA 94158-2532, USA. Tel.: +1 415 514 4420; fax: +1 415 514 2550.
Albert P. Chen
- Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA
Matthew L. Zierhut
- Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA
- UCSF/UCB Joint Graduate Group in Bioengineering, University of California San Francisco, San Francisco, CA 94158, USA
Robert A. Bok
- Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA
Charles H. Cunningham
- Department of Medical Biophysics, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada M56 2M9
John Kurhanewicz
- Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA
- Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA 94158, USA
Daniel B. Vigneron
- Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA
- Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA 94158, USA
Sarah J. Nelson
- Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA
- Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA 94158, USA

Received 5 February 2009; received in revised form 12 May 2009; accepted 4 July 2009. published online 20 August 2009.

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This article was presented in part at the 16th Annual Meeting of ISMRM, Toronto, Ontario, Canada, 2008.

☆ This research was supported by NIH grants R01-EB007588, R21-EB005363 and R01-CA111291, and UC Discovery grants LSIT01-10107 and ITL-BIO04-10148 in conjunction with GE Healthcare.

PII: S0730-725X(09)00180-5

doi:10.1016/j.mri.2009.07.007

« Previous Next »Magnetic Resonance Imaging
Volume 28, Issue 2 , Pages 153-162, February 2010

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