Magnetic Resonance Imaging
Volume 28, Issue 2 , Pages 195-199, February 2010

Time-resolved contrast-enhanced coronary magnetic resonance angiography with highly constrained projection reconstruction

  • Lan Ge

      Affiliations

    • Department of Radiology, Northwestern University, Chicago, IL 60611, USA
    • Department of Biomedical Engineering, Northwestern University, Chicago, IL 60611, USA
  • ,
  • Xiaoming Bi

      Affiliations

    • Department of Radiology, Northwestern University, Chicago, IL 60611, USA
    • Department of Biomedical Engineering, Northwestern University, Chicago, IL 60611, USA
  • ,
  • Peng Lai

      Affiliations

    • Department of Radiology, Northwestern University, Chicago, IL 60611, USA
    • Department of Biomedical Engineering, Northwestern University, Chicago, IL 60611, USA
  • ,
  • Debiao Li

      Affiliations

    • Department of Radiology, Northwestern University, Chicago, IL 60611, USA
    • Department of Biomedical Engineering, Northwestern University, Chicago, IL 60611, USA
    • Corresponding Author InformationCorresponding author. Department of Radiology, Northwestern University, Chicago, IL 60611, USA. Tel.: +1 312 926 4245; fax: +1 312 896 5665.

Received 29 March 2009; accepted 12 August 2009. published online 25 September 2009.

Abstract 

Contrast-enhanced magnetic resonance angiography (MRA) is a promising technique for coronary artery imaging. The blood signal changes during the contrast injection will result in image artifacts, blurring and relatively low signal-to-noise ratio, when the k-space segments from different cardiac cycles are combined to reconstruct the final image as “time averaged.” Thus, it is important to acquire data during maximal blood signal enhancement for first-pass, contrast-enhanced MRA, and relatively high temporal resolution is required. This work demonstrated the feasibility of highly constrained backprojection reconstruction for time-resolved, contrast-enhanced coronary MRA. With this method, the temporal resolution can be increased. In addition, coronary artery images around blood signal enhancement peak have significantly improved contrast-to-noise ratio and suppressed artifacts compared to the composite images which were collected during a much longer acquisition time during substantial blood signal changes.

Keywords: Magnetic resonance imaging, MRA, HYPR

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PII: S0730-725X(09)00198-2

doi:10.1016/j.mri.2009.08.001

Magnetic Resonance Imaging
Volume 28, Issue 2 , Pages 195-199, February 2010