Magnetic Resonance Imaging
Volume 28, Issue 2 , Pages 212-216 , February 2010

Diffusion tensor imaging in horizontal gaze palsywith progressive scoliosis

  • Ashwin Avadhani

      Affiliations

    • Department of Spine Surgery, Ganga Hospital, Coimbatore - 641043, India
  • ,
  • V. Ilayaraja

      Affiliations

    • Department of Radiology, Ganga Hospital, Coimbatore - 641043, India
  • ,
  • Ajoy P. Shetty

      Affiliations

    • Department of Spine Surgery, Ganga Hospital, Coimbatore - 641043, India
  • ,
  • S. Rajasekaran

      Affiliations

    • Department of Spine Surgery, Ganga Hospital, Coimbatore - 641043, India
    • Corresponding Author InformationCorresponding author. Department of Orthopedic and Spine Surgery, Ganga Hospital, Coimbatore - 641043, India. Tel.: +914222485000; fax: +91422245144.

Received 10 September 2009 ,Accepted 27 October 2009.

References 

  1. Jen JC, Chan WM, Bosley TM, Wan J, Carr JR, Rub U, et al. Mutations in a human ROBO gene disrupt hindbrain axon pathway crossing and morphogenesis. Science. 2004;304:1509–1513
  2. Engle EC, Leigh RJ. Genes, brainstem developmental, and eye movements. Neurology. 2002;59:304–305
  3. Rossi A, Catala M, Biancheri R, Di Comite R, Tortori-Donati P. MR imaging of brain-stem hypoplasia in horizontal gaze palsy with progressive scoliosis. Am J Neuroradiol. 2004;25:1046–1048
  4. Bomfim RC, Távora DG, Nakayama M, Gama RL. Horizontal gaze palsy with progressive scoliosis: CT and MR findings. Pediatr Radiol. 2009;39:184–187
  5. dos Santos AV, Matias S, Saraiva P, Goulão A. MR imaging features of brain stem hypoplasia in familial horizontal gaze palsy and scoliosis. Am J Neuroradiol. 2006;27:1382–1383
  6. Sicotte NL, Salamon G, Shattuck DW, Hageman N, Rub U, Salamon N, et al. Diffusion tensor MRI shows abnormal brainstem crossing fibers associated with ROBO3 mutations. Neurology. 2006;67:519–521
  7. Mori H, Fujishiro T, Hayashi N, Masutani Y, Aoki S, Ohtomo K, et al. Partially uncrossed pyramidal tracts shown by tractography in horizontal gaze palsy and scoliosis. Am J Roentgenol. 2005;184(3 Suppl):S4–S6
  8. Haller S, Wetzel SG, Lütschg J, Functional MRI. DTI and neurophysiology in horizontal gaze palsy with progressive scoliosis. Neuroradiology. 2008;50:453–459
  9. Seeger M, Tear G, Ferres-Marco D, Goodman CS. Mutations affecting growth cone guidance in Drosophila: genes necessary for guidance toward or away from the midline. Neuron. 1993;10:409–426
  10. Bosley TM, Salih MA, Jen JC, Lin DD, Oystreck D, Abu-Amero KK, et al. Neurologic features of horizontal gaze palsy and progressive scoliosis with mutations in ROBO3. Neurology. 2005;64:1196–1203
  11. MacDonald DB, Streletz LJ, Al-Zayed Z, Abdool S, Stigsby B. Intraoperative neurophysiologic discovery of uncrossed sensory and motor pathways in a patient with horizontal gaze palsy and scoliosis. Clin Neurophysiol. 2004;115:576–582
  12. Marillat V, Sabatier C, Failli V, Matsunaga E, Sotelo C, Tessier-Lavigne M, et al. The slit receptor Rig-1/Robo3 controls midline crossing by hindbrain precerebellar neurons and axons. Neuron. 2004;43:69–79

PII: S0730-725X(09)00288-4

doi: 10.1016/j.mri.2009.10.004

Magnetic Resonance Imaging
Volume 28, Issue 2 , Pages 212-216 , February 2010