Implementation and evaluation of simultaneous video-electroencephalography and functional magnetic resonance imaging

Chaudhary, Umair J.; Kokkinos, Vasileios; Carmichael, David W.; Rodionov, Roman; Gasston, David; Duncan, John S.; Lemieux, Louis

doi:10.1016/j.mri.2010.01.001

« Previous Next »Magnetic Resonance Imaging
Volume 28, Issue 8 , Pages 1192-1199, October 2010

Implementation and evaluation of simultaneous video-electroencephalography and functional magnetic resonance imaging

Umair J. Chaudhary
- Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK
- MRI Unit, National Society for Epilepsy, Chesham Lane, Chalfont St Peter, SL9 0RJ Buckinghamshire, UK
Vasileios Kokkinos
- Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK
- MRI Unit, National Society for Epilepsy, Chesham Lane, Chalfont St Peter, SL9 0RJ Buckinghamshire, UK
David W. Carmichael
- Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK
- MRI Unit, National Society for Epilepsy, Chesham Lane, Chalfont St Peter, SL9 0RJ Buckinghamshire, UK
Roman Rodionov
- Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK
- MRI Unit, National Society for Epilepsy, Chesham Lane, Chalfont St Peter, SL9 0RJ Buckinghamshire, UK
David Gasston
- Section of Cognitive Neuropsychiatry, Institute of Psychiatry, Kings College London, SE5 8AF London, UK
John S. Duncan
- Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK
- National Hospital for Neurology and Neurosurgery, Queen Square, WC1N 3BG London, UK
- MRI Unit, National Society for Epilepsy, Chesham Lane, Chalfont St Peter, SL9 0RJ Buckinghamshire, UK
Louis Lemieux
- Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, University College London, Queen Square, WC1N 3BG London, UK
- MRI Unit, National Society for Epilepsy, Chesham Lane, Chalfont St Peter, SL9 0RJ Buckinghamshire, UK
- Corresponding author. Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, Queen Square, WC1N 3BG London, UK. Tel.: +44 1494 601 361; fax: +44 1494 875 666.

Received 15 September 2009; received in revised form 22 December 2009; accepted 8 January 2010. published online 17 March 2010.

Abstract

The objective of this study was to demonstrate that the addition of simultaneous and synchronised video to electroencephalography (EEG)-correlated functional magnetic resonance imaging (fMRI) could increase recorded information without data quality reduction. We investigated the effect of placing EEG, video equipment and their required power supplies inside the scanner room, on EEG, video and MRI data quality, and evaluated video-EEG-fMRI by modelling a hand motor task. Gradient-echo, echo-planner images (EPI) were acquired on a 3-T MRI scanner at variable camera positions in a test object [with and without radiofrequency (RF) excitation], and human subjects. EEG was recorded using a commercial MR-compatible 64-channel cap and amplifiers. Video recording was performed using a two-camera custom-made system with EEG synchronization. An in-house script was used to calculate signal to fluctuation noise ratio (SFNR) from EPI in test object with variable camera positions and in human subjects with and without concurrent video recording. Five subjects were investigated with video-EEG-fMRI while performing hand motor task. The fMRI time series data was analysed using statistical parametric mapping, by building block design general linear models which were paradigm prescribed and video based. Introduction of the cameras did not alter the SFNR significantly, nor did it show any signs of spike noise during RF off conditions. Video and EEG quality also did not show any significant artefact. The Statistical Parametric Mapping{T} maps from video based design revealed additional blood oxygen level-dependent responses in the expected locations for non-compliant subjects compared to the paradigm prescribed design. We conclude that video-EEG-fMRI set up can be implemented without affecting the data quality significantly and may provide valuable information on behaviour to enhance the analysis of fMRI data.