Magnetic Resonance Imaging
Volume 28, Issue 7 , Pages 971-981, September 2010

The characterisation of mammalian tissue with 2D relaxation methods

  • Joshua Warner

      Affiliations

    • Institute of Food Research, Norwich Research Park, Colney, NR4 7UA Norwich, UK
  • ,
  • Simon Donell

      Affiliations

    • Norfolk and Norwich University Hospital, Colney, NR4 7UY Norwich, UK
  • ,
  • Kevin Wright

      Affiliations

    • Institute of Food Research, Norwich Research Park, Colney, NR4 7UA Norwich, UK
  • ,
  • Luca Venturi

      Affiliations

    • Institute of Food Research, Norwich Research Park, Colney, NR4 7UA Norwich, UK
  • ,
  • Brian Hills

      Affiliations

    • Institute of Food Research, Norwich Research Park, Colney, NR4 7UA Norwich, UK
    • Corresponding Author InformationCorresponding author.

Received 23 September 2009; received in revised form 26 February 2010; accepted 5 March 2010.

Abstract 

The potential of two-dimensional (2D) relaxometry for characterising mammalian tissue is explored on samples of liver, kidney (cortex, medulla and ureter) as well as cartilage. Significant differences are found between the T1-T2 spectra of healthy and diseased human cartilage which suggests that 2D relaxometry could have potential use in clinical diagnosis. The effect of reducing the recovery delay on the T1-T2 spectrum is explored to try to identify the optimum balance between speed and accuracy.

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PII: S0730-725X(10)00078-0

doi:10.1016/j.mri.2010.03.015

Magnetic Resonance Imaging
Volume 28, Issue 7 , Pages 971-981, September 2010