Magnetic Resonance Imaging
Volume 28, Issue 7 , Pages 919-927 , September 2010

Quantitative analysis of arterial spin labeling FMRI data using a general linear model

  • Luis Hernandez-Garcia

      Affiliations

    • Functional MRI laboratory, University of Michigan, MI 48109, USA
    • Department of Biomedical Engineering, University of Michigan, MI 48109, USA
    • Corresponding Author InformationCorresponding author. fMRI Laboratory, Ann Arbor, MI 48109-2108, USA. Tel.: +1 734 763 9254.
    • ,
  • Hesamoddin Jahanian

      Affiliations

    • Functional MRI laboratory, University of Michigan, MI 48109, USA
    • Department of Biomedical Engineering, University of Michigan, MI 48109, USA
    • ,
  • Daniel B. Rowe

      Affiliations

    • Department of Mathematics, Statistics and Computer Science, Marquette University, WI 53233, USA
    • Department of Biophysics, Medical College of Wisconsin, WI 53226, USA

Received 28 November 2009 ,Revised 16 February 2010 ,Accepted 5 March 2010.

References 

  1. Carmichael DW, Hamandi K, Laufs H, Duncan JS, Thomas DL, Lemieux L. An investigation of the relationship between BOLD and perfusion signal changes during epileptic generalised spike wave activity. Magn Reson Imaging. 2008;26:870–873
  2. Detre JA, Wang J, Wang Z, Rao H. Arterial spin-labeled perfusion MRI in basic and clinical neuroscience. Curr Opin Neurol. 2009;22:348–355
  3. Lui S, Parkes LM, Huang X, Zou K, Chan RC, Yang H, et al. Depressive disorders: focally altered cerebral perfusion measured with arterial spin-labeling MR imaging. Radiology. 2009;251:476–484
  4. Xu G, Antuono PG, Jones J, Xu Y, Wu G, Ward D, et al. Perfusion fMRI detects deficits in regional CBF during memory-encoding tasks in MCI subjects. Neurology. 2007;69:1650–1656
  5. Dai W, Lopez OL, Carmichael OT, Becker JT, Kuller LH, Gach HM. Mild cognitive impairment and Alzheimer disease: patterns of altered cerebral blood flow at MR imaging. Radiology. 2009;250:856–866
  6. Kim J, Whyte J, Wang J, Rao H, Tang KZ, Detre JA. Continuous ASL perfusion fMRI investigation of higher cognition: quantification of tonic CBF changes during sustained attention and working memory tasks. Neuroimage. 2006;31:376–385
  7. Restom K, Bangen KJ, Bondi MW, Perthen JE, Liu TT. Cerebral blood flow and BOLD responses to a memory encoding task: a comparison between healthy young and elderly adults. Neuroimage. 2007;37:430–439
  8. Williams D, Detre J, Leigh J, Koretsky A. Magnetic resonance imaging of perfusion using spin inversion of arterial water. Proc Natl Acad Sci USA. 1992;89:212–216
  9. Alsop D, Detre J. Reduced transit-time sensitivity in noninvasive magnetic resonance imaging of human cerebral blood flow. J Cereb Blood Flow Metab. 1996;16:1236–1249
  10. Wang J, Alsop D, Li L, Listerud J, Gonzalez-At J, Schnall M, et al. Comparison of quantitative perfusion imaging using arterial spin labeling at 1.5 and 4.0 Tesla. Magn Reson Med. 2002;48:242–254
  11. Hernandez-Garcia L, Lee GR, Vazquez AL, Noll DC. Fast, pseudo-continuous arterial spin labeling for functional imaging using a two-coil system. Magn Reson Med. 2004;51:577–585
  12. Liu T, Wong E, Frank L, Buxton R. Analysis and design of perfusion-based event-related fMRI experiments. Neuroimage. 2002;16:269–282
  13. Miller K, Luh W, Liu T, Martinez A, Obata T, Wong E, et al. Nonlinear temporal dynamics of the cerebral blood flow response. Hum Brain Mapp. 2001;13:1–12
  14. Liu Z, Zhou H, Wu H. A rapid method of eddy current compensation in magnetic resonance imaging systems. Zhongguo Yi Liao Qi Xie Za Zhi. 2005;29:410–413
  15. Mumford JA, Hernandez-Garcia L, Lee GR, Nichols TE. Estimation efficiency and statistical power in arterial spin labeling fMRI. Neuroimage. 2006;33:103–114
  16. Woolrich MW, Chiarelli P, Gallichan D, Perthen J, Liu TT. Bayesian inference of hemodynamic changes in functional arterial spin labeling data. Magn Reson Med. 2006;56:891–906
  17. Bevington PR, Robinson DK. Data reduction and error analysis for the physical sciences. 3rd ed.. Boston: McGraw-Hill; 2003;
  18. Aguirre G, Detre J, Zarahn E, Alsop D. Experimental design and the relative sensitivity of BOLD and perfusion fMRI. Neuroimage. 2002;15:488–500
  19. Liu T, Wong E. A signal processing model for arterial spin labeling functional MRI. Neuroimage. 2005;24:207–215
  20. Stanisz G, Odrobina E, Pun J, Escaravage M, Graham S, Bronskill M, et al. T1, T2 relaxation and magnetization transfer in tissue at 3T. Magn Reson Med. 2005;54:507–512
  21. Lu H, Clingman C, Golay X, van Zijl P. Determining the longitudinal relaxation time (T1) of blood at 3.0 Tesla. Magn Reson Med. 2004;52:679–682
  22. Dai W, Garcia D, de Bazelaire C, Alsop DC. Continuous flow-driven inversion for arterial spin labeling using pulsed radio frequency and gradient fields. Magn Reson Med. 2008;60:1488–1497

PII: S0730-725X(10)00098-6

doi: 10.1016/j.mri.2010.03.035

Magnetic Resonance Imaging
Volume 28, Issue 7 , Pages 919-927 , September 2010

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