Magnetic Resonance Imaging
Volume 28, Issue 7 , Pages 928-935 , September 2010

On the sensitivity of ASL MRI in detecting regional differences in cerebral blood flow

  • Sina Aslan

      Affiliations

    • Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    • Biomedical Engineering Graduate Program, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    • ,
  • Hanzhang Lu

      Affiliations

    • Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    • Biomedical Engineering Graduate Program, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    • Corresponding Author InformationCorresponding author. Advanced Imaging Research Center, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA. Tel.: +1 214 645 2761; fax: +1 214 645 2744.

Received 22 December 2009 ,Revised 9 March 2010 ,Accepted 14 March 2010.

References 

  1. Carrera E, Maeder-Ingvar M, Rossetti AO, Devuyst G, Bogousslavsky J. Trends in risk factors, patterns and causes in hospitalized strokes over 25 years: the Lausanne Stroke Registry. Cerebrovasc Dis. 2007;24(1):97–103
  2. Weiss JS, Sumpio BE. Review of prevalence and outcome of vascular disease in patients with diabetes mellitus. Eur J Vasc Endovasc Surg. 2006;31(2):143–150
  3. Nagata K, Maruya H, Yuya H, Terashi H, Mito Y, Kato H, et al. Can PET data differentiate Alzheimer's disease from vascular dementia?. Ann N Y Acad Sci. 2000;903:252–261
  4. Roy CS, Sherrington CS. On the regulation of the blood-supply of the brain. J Physiol 1890;11(1-2):85-158 117.
  5. Sherrington CS. Further note on degenerations following lesions of the cerebral cortex. J Physiol. 1890;11(4-5):399–400
  6. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL. A default mode of brain function. Proc Natl Acad Sci U S A. 2001;98(2):676–682
  7. Fox PT, Raichle ME. Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects. Proc Natl Acad Sci U S A. 1986;83(4):1140–1144
  8. Ogawa S, Lee TM, Kay AR, Tank DW. Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc Natl Acad Sci U S A. 1990;87(24):9868–9872
  9. Eisenberg DP, Sarpal D, Kohn PD, Meyer-Lindenberg A, Wint D, Kolachana B, et al. Catechol-O-methyltransferase valine(158)methionine genotype and resting regional cerebral blood flow in medication-free patients with schizophrenia. Biol Psychiatry. 2010;67(3):287–290
  10. Johnson NA, Jahng GH, Weiner MW, Miller BL, Chui HC, Jagust WJ, et al. Pattern of cerebral hypoperfusion in Alzheimer disease and mild cognitive impairment measured with arterial spin-labeling MR imaging: initial experience. Radiology. 2005;234(3):851–859
  11. Derejko M, Slawek J, Lass P, Nyka WM. Cerebral blood flow changes in Parkinson's disease associated with dementia. Nucl Med Rev Cent East Eur. 2001;4(2):123–127
  12. Schuff N, Matsumoto S, Kmiecik J, Studholme C, Du A, Ezekiel F, et al. Cerebral blood flow in ischemic vascular dementia and Alzheimer's disease, measured by arterial spin-labeling magnetic resonance imaging. Alzheimers Demen. 2009;5(6):454–462
  13. Mintun MA, Raichle ME, Martin WR, Herscovitch P. Brain oxygen utilization measured with O-15 radiotracers and positron emission tomography. J Nucl Med. 1984;25(2):177–187
  14. Devous MD, Stokely EM, Chehabi HH, Bonte FJ. Normal distribution of regional cerebral blood flow measured by dynamic single-photon emission tomography. J Cereb Blood Flow Metab. 1986;6(1):95–104
  15. Wang J, Zhang Y, Wolf RL, Roc AC, Alsop DC, Detre JA. Amplitude-modulated continuous arterial spin-labeling 3.0-T perfusion MR imaging with a single coil: feasibility study. Radiology. 2005;235(1):218–228
  16. Golay X, Hendrikse J, Lim TC. Perfusion imaging using arterial spin labeling. Top Magn Reson Imaging. 2004;15(1):10–27
  17. Detre JA, Leigh JS, Williams DS, Koretsky AP. Perfusion imaging. Magn Reson Med. 1992;23(1):37–45
  18. Williams DS, Detre JA, Leigh JS, Koretsky AP. Magnetic resonance imaging of perfusion using spin inversion of arterial water. Proc Natl Acad Sci U S A. 1992;89(1):212–216
  19. Wong EC, Buxton RB, Frank LR. Implementation of quantitative perfusion imaging techniques for functional brain mapping using pulsed arterial spin labeling. NMR Biomed. 1997;10(4-5):237–249
  20. Petersen ET, Lim T, Golay X. Model-free arterial spin labeling quantification approach for perfusion MRI. Magn Reson Med. 2006;55(2):219–232
  21. Edelman RR, Siewert B, Darby DG, Thangaraj V, Nobre AC, Mesulam MM, et al. Qualitative mapping of cerebral blood flow and functional localization with echo-planar MR imaging and signal targeting with alternating radio frequency. Radiology. 1994;192(2):513–520
  22. Kim SG. Quantification of relative cerebral blood flow change by flow-sensitive alternating inversion recovery (FAIR) technique: application to functional mapping. Magn Reson Med. 1995;34(3):293–301
  23. Liu TT, Behzadi Y, Restom K, Uludag K, Lu K, Buracas GT, et al. Caffeine alters the temporal dynamics of the visual BOLD response. Neuroimage. 2004;23(4):1402–1413
  24. Laurienti PJ, Field AS, Burdette JH, Maldjian JA, Yen YF, Moody DM. Relationship between caffeine-induced changes in resting cerebral perfusion and blood oxygenation level-dependent signal. AJNR Am J Neuroradiol. 2003;24(8):1607–1611
  25. Cohen ER, Ugurbil K, Kim SG. Effect of basal conditions on the magnitude and dynamics of the blood oxygenation level-dependent fMRI response. J Cereb Blood Flow Metab. 2002;22(9):1042–1053
  26. Wu WC, Fernandez-Seara M, Detre JA, Wehrli FW, Wang J. A theoretical and experimental investigation of the tagging efficiency of pseudocontinuous arterial spin labeling. Magn Reson Med. 2007;58(5):1020–1027
  27. Wong EC. Vessel-encoded arterial spin-labeling using pseudocontinuous tagging. Magn Reson Med. 2007;58(6):1086–1091
  28. Aslan SXF, Wang PL, Uh J, Yezhuvath U, van Osch M, Lu H. Estimation of labeling efficiency in pseudo-continuous arterial spin labeling. Magn Reson Med. 2010;63(3):765–771
  29. Tzourio-Mazoyer N, Landeau B, Papathanassiou D, Crivello F, Etard O, Delcroix N, et al. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage. 2002;15(1):273–289
  30. Ashburner J, Friston KJ. Voxel-based morphometry — the methods. Neuroimage. 2000;11(6 Pt 1):805–821
  31. Alsop DC, Detre JA, Grossman M. Assessment of cerebral blood flow in Alzheimer's disease by spin-labeled magnetic resonance imaging. Ann Neurol. 2000;47(1):93–100
  32. Theberge J. Perfusion magnetic resonance imaging in psychiatry. Top Magn Reson Imaging. 2008;19(2):111–130
  33. Lavy S, Melamed E, Cooper G, Bentin S, Rinot Y. Regional cerebral blood flow in patients with Parkinson's disease. Arch Neurol. 1979;36(6):344–348
  34. Dousse M, Mamo H, Ponsin JC, Tran Dinh Y. Cerebral blood flow in schizophrenia. Exp Neurol. 1988;100(1):98–111
  35. Parkes LM, Rashid W, Chard DT, Tofts PS. Normal cerebral perfusion measurements using arterial spin labeling: reproducibility, stability, and age and gender effects. Magn Reson Med. 2004;51(4):736–743

☆ Grant Sponsors: NIH R01 MH084021, NIH R21 EB007821, NIH R21 AG034318, Department of Veterans Affairs VA549P0027

PII: S0730-725X(10)00100-1

doi: 10.1016/j.mri.2010.03.037

Magnetic Resonance Imaging
Volume 28, Issue 7 , Pages 928-935 , September 2010

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